tag:blogger.com,1999:blog-655962722302095847.post611094626242273927..comments2024-03-27T20:20:54.505+01:00Comments on Epiphany: Piracetam for Autism, ComradesPeter Lloyd-Thomashttp://www.blogger.com/profile/10173383229834614994noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-655962722302095847.post-32807981237421311012015-01-31T17:10:17.053+01:002015-01-31T17:10:17.053+01:00I think you can just try it and see. It seems tha...I think you can just try it and see. It seems that about half of people with autism respond to Bumetanide. Peter Lloyd-Thomashttps://www.blogger.com/profile/10173383229834614994noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-50222100710524055062015-01-31T12:06:20.791+01:002015-01-31T12:06:20.791+01:00Hi Peter, and thanks again for this fantastic site...Hi Peter, and thanks again for this fantastic site. I've finally been diagnosed with adhd inattentive with autistic traits, although I'm absolutely confident dyspraxia/DCD is the most appropriate description.<br /><br />I'm currently trying 2mg of Bumetanide daily. Do you think it has any effect on the DCD spectrum of autism? I have yet to try piracetam. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-20278821248873282452014-04-03T04:56:41.513+02:002014-04-03T04:56:41.513+02:00Piracetam is to be in theory- a "Cognitive En...Piracetam is to be in theory- a "Cognitive Enhancer". I have an Autism Spectrum Disorder, though I have no idea what this medication would do to me. I bought some Piracetam, Choline, and fish oil off the web... We shall see rabbit. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-2390500286149584902013-11-14T21:44:33.691+01:002013-11-14T21:44:33.691+01:00Interestingly, the nicotinic receptors in the chol...Interestingly, the nicotinic receptors in the cholinergic system function in one (good) way when given a low level of stimulation; but at high levels the effect is completely lost. So it looks like 2-3 cigarettes a day may have a genuine health benefit. If you smoke 20 then the receptors are overloaded and you lose the anti-inflamatory benefits, but you get the "high".Peter Lloyd-Thomashttps://www.blogger.com/profile/10173383229834614994noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-72510892949544006032013-11-14T21:37:36.049+01:002013-11-14T21:37:36.049+01:00The problem with testing electrolytes and hormones...The problem with testing electrolytes and hormones is that you are limited to the blood. What is happening in the brain may actually be the opposite, so Free T3 thyroid hormone can be high in the blood but low in the brain. My son has high serotonin in the blood, but I am pretty sure it is low in the brain. I am discussing this with an Endocrinologist, and I am getting her to point that she can see my logic that there is central hormone dysfunction (inversion) in autism. I am reading about Magnesium and here again it seems that low brain levels of magnesium are common in many neurological/psychiatric conditions; because of the blood brain barrier, low brain magnesium may be accompanied by normal or even elevated blood levels.<br /><br />I have not considered the thymus (yet).<br /><br />It really looks like there is complete failure to maintain the homeostasis of hormones and intra/extracellular levels of electrolytes in the brain. It is amazing the brain continues to function. Na, K and Mg are all interrelated so it is logical that Na is not good for you. But Mg should help maintain your K levels. <br /><br />The thing I like about Piracetam is the lack of virtually any side effects. So you cannot do any harm, unlike many other drugs that do actually have some benefits but have side effects. Piracetam is cheap and does have a positive effect, as do the nicotine patches incidentally. If you want to increase the effect of Piracetam you add choline. This done by both researchers and "cognitive enhancers".<br />Peter Lloyd-Thomashttps://www.blogger.com/profile/10173383229834614994noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-9000617460736206912013-11-14T20:15:56.437+01:002013-11-14T20:15:56.437+01:00Thank you for this insightful article I have never...Thank you for this insightful article I have never heard of nootropics until I read your article here.. I commented before I believe on a blog about sensory overload and rare adhd caused by low potassium levels.. I have a rare (supposedly) disorder named Andersen tawil syndrome and believe it goes through five generations of my family.. Even though my potassium is not considered low I become very ill when my levels are below 4.5 and feel well at 5.5.. over the course of 53 years of life with hypokalemic illness I feel I have lost a lot of my mental sharpness.. and have described my symptoms as brain fog to the 9nth degree.. I think perhaps the Piracetem might be something I ought to try.. when I read the research about Viagra being helpful for oxygenation I was curious about trying that but with cost and likelihood that my doctor wouldn't prescribe it for my off label use anyway I gave that up.. Some of the individuals I have met have had some success with mestinon for some of there issues exacerbated by hypokalemic symptoms even though our levels are almost always wnl.. another friend has recently undergone a thymectomy and has had substantial improvement with this surgery .. have you ever given consideration to the role of the thymus in autism? My daughter has a dual diagnosis of PP possible Andersen tawil syndrome and Aspergers syndrome.. Even though my potassium is always within normal levels (so far) I ingest on an average of 100 meq of khlor con daily along with 80 mg of accupril (potassium sparing) to hold my levels artificially higher along with a low carb diet as even small shifts of my potassium lower can cause horrendous brain fog.. muscle pain muscle weakness and paralysis.. I agree with your new focus on endocrinology in my very ill family members many are very short and many are very tall .. but many also both extremes have various levels of physical and nuerological deficits varying from sensory integration problems to adhd .. so very many complex issues.. I am also curious about mitochondrial issues as others I have met often exhibit severe gastroparesis along with mitochondrial issues.. and ps.. most of us are descended from sick royal ancestors with the Habsburgs being at the top of the family heap poor Charles had supposedly Renal Tubular Acidosis and pituitary issues I believe.. I continue to read your research and I believe you are definitely on the right track.. One more thing I wanted to mention for me sodium is one of my worst triggers,, plus even minor fluctuations in my potassium in the downward direction can trigger me so for me along with the potassium in massive quantities the ace inhibitors sugar and refined carbs can trigger a worsening of my symptoms.. so even though considered a good source of potassium potatoes.. bananas and sweat potatoes the carb load completely negates the potassium content in my case.. thank you againkattsqueenhttps://www.blogger.com/profile/13842561133805804035noreply@blogger.com