tag:blogger.com,1999:blog-655962722302095847.post4425285885495404047..comments2024-03-27T20:20:54.505+01:00Comments on Epiphany: Preventing Auto-Immune Disease and some AutismPeter Lloyd-Thomashttp://www.blogger.com/profile/10173383229834614994noreply@blogger.comBlogger40125tag:blogger.com,1999:blog-655962722302095847.post-91914241580856005582016-11-25T15:25:48.587+01:002016-11-25T15:25:48.587+01:00Hello Peter,
Had gone for a week's stay to my...Hello Peter,<br /><br />Had gone for a week's stay to my parents place without the bioamicus reuteri and my son's social behaviour seemed to deteriorate a little. Now we are a strongly opinionated, a little loud family, where every one thinks that everybody else is a fool and the only circumstance under which you will find any two members having an amicable discussion is when they are criticizing a third one. So there is lot of energy flying and flowing around and probably that adds to my son's lousy behaviour and tantrums or it could have been a combination of things. He was just acting like a spoilt brat and I was thinking of what lies ahead.<br /><br />Back home, and after day and a half of the probiotic, he seems back to normal. The probiotic took effect only after some digestive issues which led to gas were resolved. So you see, it is such a delicate balance and any intervention will give it's greatest benefit only when my son has an absolutely clean intestine. My husband watching my son struggling and tantrumming with his studies two days back felt that we should add back bumetsnide. But you see, with indigestion relieved, yesterday he did quite well.<br /><br />Coming to after effects of bumetanide withdrawal, things seem to have just stuck..all kinds of things.<br /><br />Cognitive gains seem to have stuck. Better handwriting and good pencil grip. Some kind of enhancement in gross motor skills..his movements. He never had issues with those but a little more body awareness. Developing ability to catch and follow a beat. I patted on his feet..12-123, and he matched the beat with a clap. This was new. And I asked him to spell cat, and as I started with c he added a and t. Same with bat. The best part is his group of teachers at the therapy center have noticed improvements across board. <br /><br />And for me, the best part was when he planned out an attempt to hold our Alexandrian parakeet at my parents place using a napkin as our parrot was in an aggressive mood. Then he put his hands behind him and just tried to reach him with a kiss, accurately mimicking the parrots actions with the menacing open beak and curled tongue. His interactions with our dog are also more purposeful and affectionate.<br /><br />But the downside is that visual stimming that he developed on bumetanide is not going away. And probably I had mentioned earlier, he is performing a curious act of running from switch board to switch board, stopping in front of each to gaze at the holes. This is a really mad act but I had read an autobiography written jointly by a morher-son, where the autistic son improved dramatically later in life and this child used to do the same wondering where these holes lead to and how and if they are connected. Probably wishful thinking on my part but what else can I do.<br /><br />So Peter, in my son, even intermittent treatments leave some lasting impacts. And which include both negative and positive ones. Probably bumetsnide just disturbed his electrolyte balance and it might be a while before they are restored. <br /><br />I am certain that even a good detox and antiinflammatory regime will support him with his natural progress. Wondering if I should trial clonazepam as I am wary of going for another round of diuretics till his sensitivities settle down. Or just start with antiinflammatories like kutki, taurine and low dose methylfolate. <br /><br /><br />Trying to arrange for cardiazol. Let's see. <br /><br />Do suggest if something crosses your mind.<br /><br />Kritikanoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-68913774655561306742016-11-23T17:52:09.616+01:002016-11-23T17:52:09.616+01:00Sorry for the wrong spelling..it's reserpine a...Sorry for the wrong spelling..it's reserpine and not resperine..extracted from Rauwolfia serpentinaKritikanoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-79286552673024723692016-11-23T15:45:40.963+01:002016-11-23T15:45:40.963+01:00Hello Peter,
Came across a few reports promoting ...Hello Peter,<br /><br />Came across a few reports promoting and of obviously, demoting or dismissing and even warning against the use of resperine for autism, a therapy I think which got some publicity around 2010.<br /><br />What caught my interest was an attempt at scientifically explaining why it might work for some autism. Women with a family history of depression, who get an epidural and pitocin during delivery if birthing male child might distort the enzymatic activity or levels of monoamine oxidase which supposedly plays critical role in conversions of certain neurotransmitters into their activated forms.<br /><br />I did not really understand the entire hypothesis but I got an epidural and pitocin and probably was assisted with a vacuum as I remember the gynae who was in a real hurry to wind up telling me that she can see the babies head and it should be just a push or two. But after that I saw the nurse carrying something like a pump..there was an immediate birth cry and in the discharge summary it was written as NVD. And from my father's side we have what can be called as depression in some members but they mask it or rather, treat themselves by surrounding themselves with family and pets.<br /><br />What would be your views be on MAO and could their be safer ways to increase its levels in the child as resperine is a psychoactive drug extracted from a plant hailing from, once again, India.<br />Kritikanoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-66390728552462617732016-11-20T18:30:39.608+01:002016-11-20T18:30:39.608+01:00Kritika, I am glad it was you that noted the link ...Kritika, I am glad it was you that noted the link between education and risk of autism. Nobody is going to research this, but look at how many very clever people (professors etc) have relatives with autism. If you looked at what happens when educated alpha male marries educated alpha female I think you would see the same. You might then conclude that going to work in a stressful job while pregnant is unwise for those with other risk factors. I think this will only apply to some sub-types of autism. There will be many kids with autism whose parents are not rocket scientists. <br /><br />Clearly stress is not good for you and the unborn child is not as robust as we might have thought, and needs protection.Peter Lloyd-Thomashttps://www.blogger.com/profile/10173383229834614994noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-59409797922731059492016-11-20T17:40:38.524+01:002016-11-20T17:40:38.524+01:00Hi Kritika,
Doctor didn't mention if his twin ...Hi Kritika,<br />Doctor didn't mention if his twin brother is identical.<br /><br />I also suspect maternal "brain burning" profile, as you very well put it, has something to do with autism and neurological diseases.<br />Having the tendency to (ab)use your brain sometimes lead women to a higher education pursue and maybe this is part of the "inflammation". Ruminating, problem solving, putting things in order, while recognizing the chaos and observe yourself and others playing different roles in an attempt to represent life...constantly moving brain.<br />I believe MIA model could be a usuful scientific tool as long as you can identify your phenotype there. I don't get offended, it's not a "witch hunting" issue.<br />Whenever I am put into the MIA model it's not me as a subject with hundreds of expressions,it's me as an object charged with particular non qualities. They can make me obese, anorectic, smoker, alcohol/drug abuser, refrigerated, disordered, whatever.. MIA model is a lab condition, and as Peter I think says, it's strange in how many ways they can make mice autistic. Practically nothing is as stable as that and mum is changing all the time, before, during, after pregnancy, but I can accept that the emotional and physical stress remains.<br />Metaphysical and deterministical explanations usually don't lead me anywhere.Anonymoushttps://www.blogger.com/profile/16138974464162606874noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-30258779633090302632016-11-20T03:01:08.414+01:002016-11-20T03:01:08.414+01:00Thank you for your post Christian. Could you share...Thank you for your post Christian. Could you share more please on molybenum, how much you have been taking and the effects you experienced. Natnoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-78834895310103555032016-11-19T22:07:59.469+01:002016-11-19T22:07:59.469+01:00Hi Petra,
Was curious about your doctor's bro...Hi Petra,<br />Was curious about your doctor's brother being an identical twin or otherwise.<br /><br />To further add to the chat, a doctor couple I know with a severely afflicted child with autism was recently visited by their old friends, another doctor couple who are suspecting their three year old to be autistic.<br /><br />Petra, sometimes I do wonder if females who pursue education, the real nerve wracking, rigorous, brain burning one, are more susceptible to bearing children with autism. Maternal education and maternal inflammation? It would be interesting to generate data that might link female education alone, not maternal age which might covary with it, to incidence of neurodevelopmental disorders in kids born to them.<br /><br />Did God really intend women to limit their imagination to home and hearth. I do not mean this in a negative way at all as I am quite happy to be 'just a housewife' after having gone through the rigors of higher education. What if we do find a relation between stressful education and career choices and problems with children birthed by such mothers. After years of bearing humiliation and condemned for being that unstimulating, dumb housewife who cannot think beyond the pot and the pan and bears children which is something that even animals can do and probably better, now women are facing predicament of a totally different kind. <br /><br />You are damned if you do and you are damned if you don't. Kritikanoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-34055022027460436342016-11-19T20:43:52.556+01:002016-11-19T20:43:52.556+01:00Here is some research directly pertinent to this t...Here is some research directly pertinent to this topic in that new research (no paper unfortunately as it was a presentation or the Society of Neuroscience) which discusses how allergies can increase the risk of autism and specifically what seems to happen as a result of in-utero allergy exposure:<br /><br />https://www.sciencedaily.com/releases/2016/11/161116155342.htm<br /><br />One thing I found interesting about this is that I just read a paper discussing mechanisms of PTSD and what the researchers found in that paper is that a single bout of acute stress (not chronic stress) has a lasting impact of retracting dendritic spines in the prefrontal cortex via a cascade of events following a glutamate surge as a result of the acute stress. They found these stress insults to have significant effects on spine density and morphology for several weeks which was surprising because the conventional view was that only chronic stress like you see in depression can cause these kind of pathological features in dendritic spines.Tylernoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-34667606382935464482016-11-19T20:36:04.854+01:002016-11-19T20:36:04.854+01:00I am not trying to hurt anyone's feelings here...I am not trying to hurt anyone's feelings here but diabetes/gestational diabetes and caesarean delivery (the evidenced is mixed here) are proven in multiple studies (multiple as in dozens) as providing negative neurodevelopmental outcomes (including autism) for those born under those conditions, while obesity itself is a major risk factor as well. Not to mention, obese people have worse immunity and infection during pregnancy due to a poorly functioning immune system is also strongly associated with a big increase in risk for autism.<br /><br />On top of that, there are many animal model studies now that show the multiple mechanisms about how an obese mother's poor health choices may cause harm to her children.<br /><br />This is not a male versus female issue as negative health outcomes via obesity in males has been shown to be inherited now through germline manipulation of microRNA's that get passed on to their progeny via the sperm. Of course, obesity in males has yet to be shown as damaging to the baby as obesity in females, but considering an enormous percentage of obese men (I forget the numbers) are infertile due to low sperm count and poor quality sperm, this shows the need for men and women in the west to get their butt off the couch if not for themselves, than for the fact they are harming future generations by not taking their health seriously until it is too late.<br /><br />Also, there is a big difference (no pun intended) between women having a shapely healthy figure or maybe even being a tiny bit overweight, and morbid obesity. And the logic that "well I have seen obese women without autistic children" does not fly in the face of the evidence because there are plenty of children who are born without strong symptoms of asthma or fetal alcohol syndrome as a result of their mothers smoking and drinking during pregnancy, or else being exposed to a poor environment if they end up being pregnant in a city with toxic air like Beijing.<br /><br />Really, this is just supposed to be an intellectual discussion about what is one of the biggest overlooked risk factors or perhaps even the biggest risk factor for autism in the anglo countries at the moment besides perhaps overdiagnosis relative to other nations with less sophisticated and accessible health care systems.Tylernoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-1503359921332137762016-11-19T13:36:18.627+01:002016-11-19T13:36:18.627+01:00Megan,
Do not even mention the raging hormones he...Megan, <br />Do not even mention the raging hormones here or some of the male readers will conclude that your comments with that confrontationist tone must have been written under the influence of PMS. Next thing you know somebody will come out with a study where they will link incidence of PMS, hence temporary insanity or better still, hysteria, with autistic progeny.<br /><br />Somewhere I suspect that too much 'barking up the wrong tree' is a response to the discomfort most males feel in finding great affinity with autistic traits.<br /><br />Hate to see my comment degenerating into a male versus female issue as I do feel that we can't deny biology owing to which females might be having greater influence on and hence responsibility towards the children they bear.Kritikanoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-86397688660148588302016-11-19T11:33:18.646+01:002016-11-19T11:33:18.646+01:00Hi Kritika, I appreciate your information.
Me and...Hi Kritika, I appreciate your information.<br /><br />Me and my husband don't show signs of diabets, only my mum, in an older age has had high blood sugar, not established as diabets and controls it with a pill (sitagliptin).<br />As I read now it's for diabets type 2 and usually prescribed with metformin (you can read Peter's relevant post).<br /><br />My gastrenterologist directed me for abdomen blood-urine-magnetic check up and told me to visit an endocrinologist for further investigation.<br /><br />My son was born almost 4 kilos and two weeks earlier. My niece (16y with neurological problems), from my husband's sister was also born overweight. I remember her doctor, specializing on metabolic syndroms, during neonatal examination, explaining that such babies have greater possibility to develop diabets later in life and we should keep that in mind.<br /><br />This time my gastrenterologist paid more attention to my claim that there must be a metabolic syndrom because, although he was not the one in charge to treat my son's last infection, he followed the course and got confused with my son's immune response.<br />Morover, and this may sound "chatty", still don't mention it for the chat itself but to give an example of how autism strikes in an indistinguish and indiscriminate way, Doctor told me that he suspects his almost 3 year old nephew from his twin brother to have autism but his parents don't accept it. Doctor has just had a baby and told me that he had a personal interest for my son's case report.<br />Anonymoushttps://www.blogger.com/profile/16138974464162606874noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-47710546959844360512016-11-19T02:04:34.157+01:002016-11-19T02:04:34.157+01:00You will have to find the different "biotypes...You will have to find the different "biotypes" before you can "blame" anything for autism. And, even then... But, let's go easy on Mom. We've already had the refrigerator Mom theory. Unless you've experienced being pregnant, and thinking oh, dirt sounds really yummy right now, you really don't know what it's like to want to rip the entire world's head off in one collective blow (otherwise known as PMS). Estrogen is a beast that only the most skillful can ride, and I've yet to meet a man who was up to it, though some do try. :)Anonymoushttps://www.blogger.com/profile/18395264374922583194noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-6463033633385727322016-11-19T01:44:53.792+01:002016-11-19T01:44:53.792+01:00I'm from America. Not fat. China and Japan d...I'm from America. Not fat. China and Japan do not have the "obesity epidemic" we have here in the good ole US of A, and they are still having an "autism epidemic". Especially Japan. The autism rate there was 161 out of every 10,000. That blows the rate in the US out of the water. I don't think Japan is a nation of fat people. Those numbers were from July 1, 2015 from a source called world atlas. Next, is the UK, then Sweden, then Denmark, with the US coming in 5th. There was also an article in the WSJ about China's uncounted autistic children. My husband had ADD as a child, and his Mom would have barely hit 100 pounds, soaking wet. My husband is also thin. I see lots of horribly obese women with social, "normal" children. I think we're barking up the wrong tree here. Now, I think being obese can lead to low birth weight/preemie babies. But, given that my baby that is autistic was nearly 9 pounds and 20 inches tall at birth, and full term, there has to be something else. I actually gained less weight with him than with my first "normal" child. I also breastfed. Oh, and I never drank, never used drugs. That being said, I don't think it would hurt anyone to watch what they eat a little more closely. But, I don't think obesity is the answer to the autism epidemic. Both of my children did have to be delivered via c-section. Anonymoushttps://www.blogger.com/profile/18395264374922583194noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-4312750690445154192016-11-19T01:02:10.218+01:002016-11-19T01:02:10.218+01:00Here is some very hopeful research in its early st...Here is some very hopeful research in its early stages on a potential epigenetic signature for idiopathic autism:<br /><br />http://www.cell.com/cell/abstract/S0092-8674(16)31451-9?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867416314519%3Fshowall%3Dtrue<br /><br />The ability to mass edit genes directly via tools like CRISPR/Cas9 is still in its infancy and a lot more difficult than epigenetic retooling as there has been an enormous investment in drug research for epigenetic drugs/tools for the purposes of cancer research. IF there is a common epigenetic signature for autism (a very big IF) then reversing many of the symptoms of autism or at least improving them considerably may indeed be possible and may also be treated with drugs. This is just preliminary research, but it is the first I have seen to make any claims about a common epigenetic signature that most cases of autism share.Tylernoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-79312972336064740602016-11-18T20:42:54.915+01:002016-11-18T20:42:54.915+01:00Petra,
Sometimes hypoglycemia induces a seizure l...Petra,<br /><br />Sometimes hypoglycemia induces a seizure like condition.. I remember your son had not eaten for twenty four hours. Could that have complicated things.<br /><br />My father who was on insulin to manage steroid induced diabetes used to have these sudden spikes as the body would produce insulin in a spurt and that along with the injected insulin resulted in hypoglycemia. The condition it triggered was quite similar to what you observed in your son. <br /><br />Wishing your son good health <br />Anonymoushttps://www.blogger.com/profile/03480846227414561711noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-34004670594288953202016-11-18T19:13:18.669+01:002016-11-18T19:13:18.669+01:00Oxidative stress, I agree. So few people see it as...Oxidative stress, I agree. So few people see it as fundamental to disease. In the case of ASD, I see a lot of it coming from slow SUOX, XDH, and AOX1 genetics and lack of molybdenum, either the mineral itself or molybdopterin. <br /><br />When these genes are slow there will be a build up in O2 in the mitochondria. Any electron that hist the O2 will turn them into superoxides. Note that all those genes have to do with environmental detoxification.<br /><br />I have aspergers and Molybdemun changed my life. And in all the genes I have for autistic children I see rare gene SNPs in those genes.<br /><br />Slowing SUOX will also result in a rise in glutamate since sulfites inhibit glutamate dehydrogenase.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-21291003598000684672016-11-18T12:33:10.780+01:002016-11-18T12:33:10.780+01:00At a regular check up sugar levels seem fine. I do...At a regular check up sugar levels seem fine. I do suspect prediabets and need to work on this.<br />My son is supposed to not have seizures but I doubt it. There are 180 identified kinds of seizures and probably some not identified yet.<br />I do indeed perceive all these weird things happening as seizures.Anonymoushttps://www.blogger.com/profile/16138974464162606874noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-66399353699713293472016-11-18T11:26:50.396+01:002016-11-18T11:26:50.396+01:00Petra,
Have you checked for sugar levels.. or it ...Petra,<br /><br />Have you checked for sugar levels.. or it could be a seizure? Kritikanoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-44247590789567274492016-11-18T11:16:23.350+01:002016-11-18T11:16:23.350+01:00Peter, my son is challenged with a kind of attack ...Peter, my son is challenged with a kind of attack with trembling coming from the thorax area, together with excessive sweat especially in hands?<br />I know it can be a fear response but I was wondering if there may be other implications.Anonymoushttps://www.blogger.com/profile/16138974464162606874noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-44467746588728193742016-11-18T05:35:23.887+01:002016-11-18T05:35:23.887+01:00Yes, this is so true. Both of my most afflicted ki...Yes, this is so true. Both of my most afflicted kids (I have 3 with an autism diagnosis out of 4 children) have weight problems that blew up about age 3-4 during the winter months when I could not take them for long walks. Once I started adding supplemental fiber into their diet, this helped deal with their appetites and their last pediatric checkups have shown their growth curves with weight to be stabilized/reducing relative to where they should be for their age.<br /><br />Incidentally, here is a great study I just read today (it is long but well worth the read) that showed a new mechanism of how a fiber free diet or even one without any whole plant fiber (they called it a prebiotic diet) leads to the erosion of the mucus lining the epithelium of the digestive tract due to the gut microbiota literally eating the mucus for food since there are no polysaccharides for them to munch on, due to a low fiber diet:<br /><br />http://www.cell.com/cell/abstract/S0092-8674(16)31464-7<br /><br />One of the most interesting takeaways is that they suggested that even though some prebiotics may be great for SCFA production, but they won't do much for preventing this mucus degrading effect which seems to be critical in helping to prevent disease and inflammation in the gut. The fiber supplementation I personally use is a home brew combination of potato starch, barley flour, and inulin, but in light of this research I might have to consider ways of getting my children more fiber from sources with intact plant cell walls. I will say that perhaps I am doing something right because there have been some nasty flu and colds going around in the last couple years, and my kids have almost never been sick (and neither have I). This was not the case before they got daily supplemental soluble fiber in their diet. Of course this is all anecdotal and flu season is about to hit my areas of the United States, so I could be suffering miserably from some flu or cold in the coming weeks, but I have found it strange that my family seems to have been spared a lot of misery for whatever reason. Oh yah and the only member of my family who has gotten sick off and on the most has been my wife who does not take regular supplemental fiber and does not exactly eat what I would call a healthy diet that has a lot of natural fiber in it. Again this is all anecdotal so maybe it is time to cross my fingers when the holidays roll around (-:Tylernoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-20928199835676889522016-11-18T05:12:21.807+01:002016-11-18T05:12:21.807+01:00Well I am not sure which country you said you were...Well I am not sure which country you said you were from, the here in the United States we have a lot of problems of our own making and obesity, drugs, and alcohol abuse are just some of them.<br /><br />About 20 years ago, there was a push among some in popular culture for women to "love their bodies" no matter what their body looked like. Anorexia was the big problem in the news at the time while these days you almost never hear about it anymore as the pendulum has swung to the opposite direction and some 300 pound women literally think that if anyone finds them unattractive, then there is something wrong with the people judging them. Fat shaming may have induced some people to have eating disorders such as anorexia, but it is hard to argue that it didn't also help keep obesity rates down to a level that literally does not threaten the very survival of future generations. As an example, our military is having extreme recruiting challenges because the younger generation is simply too unfit to serve even if they want to.<br /><br />Simply put, becoming obese is still not taken seriously in American culture because literally 40% of women now are obese (35% men) and 70% of women are overweight. Other than maybe Great Britain, you can't find these levels of obesity anywhere else in the world and if you track autism rates as well as the rates of ADHD, and correlate them with the increase in the rates of obesity, you see something shocking there. Of course, correlation does not mean causation, but the causative research in animal models (such as the one I just cited) is really making this a topic society cannot just ignore anymore.<br /><br />Even though obesity can be strongly inherited via genetic and epigenetic factors, treating it comes down to dealing with treating food as an addiction as plenty of studies have shown that a reduced intake of calories and moderate exercise will cause just about anyone to lose weight over time. As you lose weight you will need to decrease your calories. Also, during that time many people are miserable because dieting is not something people would typically do until the very modern age as people other than elite nobles or members of an upper caste rarely had enough food to keep them satiated all the time. The problem now is that people are not motivated to put themselves through the pain and suffering you have to go through to eat less food than your brain is telling you that you need. This is a problem of addiction and willpower and choice. Cancer patients often have the stark choice of going through the pain and suffering of chemotherapy or dying, but most choose chemotherapy unless they sincerely believe nothing else can be done. Obesity needs to be taken as seriously as cancer itself, especially since one of the greatest risk factors for all cancers is obesity itself.<br /><br />The Okinawans (an island of Japan) famously have a saying that you should always stop eating before you feel full (obviously the saying is in Japanese), and the Okinawans are some of the healthiest and long-lived people on the planet.<br /><br />Here in the United States the average expected lifetime of a person here actually decreased last year. Among white middle aged caucasian women in particular, there has been a huge decrease in life expectancy in the last decade and most attribute this to obesity, drug, and alcohol abuse among this ethnic group. Unhealthy women will produce unhealthy children and until society understands it that your health (both men and women as plenty of recent research suggests male lifestyle factors have a big impact on future progeny) is not just a matter of your own liberty, but also of responsibility to the next generation, people are not going to make the positive effort to make losing weight (and keeping it off) a priority in their lives.Tylernoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-2305197399569827152016-11-18T03:41:49.778+01:002016-11-18T03:41:49.778+01:00I have to say in autism research there is a skew t...I have to say in autism research there is a skew towards blaming Mom. In fact, it is EVERYWHERE!! Intelligence, they say, is more based on Mom, than Dad. Autism, it's more Mom than Dad. In fact, I think, based on researchers' analyses, my boys should act like me, talk like me, and basically be mini me's. But, they don't. In fact, if my mother's intelligence was the sole basis for my intelligence, I sure as hell wouldn't have been able to do multivariable calculus. That's pure Dad. In fact, even the immune activation mouse always makes me feel like I need to tilt my head and squint, like I'm looking at a skewed canvas. Women used to get sick when they were pregnant...and it didn't make anyone blink twice. Now, if only Dr. Naviaux would get his research results published. By the way, Peter, Dr. Richard Frye just published some interesting stuff about Leucovorin. Not sure if you had seen it.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-77075576504761287652016-11-17T13:50:51.316+01:002016-11-17T13:50:51.316+01:00Maternal and paternal and lots of other relatives ...Maternal and paternal and lots of other relatives eating disorders profile might also give some clues. One of some autism core symptom is in fact an eating disorder which is described as picky eating, starvation, and generally fear/anxiety of food, accompanied with periods of obesity and metabolic syndrome. Anonymoushttps://www.blogger.com/profile/16138974464162606874noreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-62372440138858663902016-11-17T13:24:59.621+01:002016-11-17T13:24:59.621+01:00Tyler,
I have read that piece about fat mother mi...Tyler,<br /><br />I have read that piece about fat mother mice, rather mother mice fed on a diet to induce obesity giving birth to pups with a different gut flora and less sociability versus mother mice fed on a regular diet with pups who were social and had l.reureri in their gi tracts.<br /><br />I am not countering that obesity or smoking or alcohol are dissociated with any risk to the progeny. <br /><br />But I have strong objection to obesity being treated as a lifestyle choice..as much as I object to your portrayal of women consuming alcohol when unable to conceive in the fear of being deserted by their husbands. Or did you write that in a lighter vein.<br /><br />I have not nothing further to add.Kritikanoreply@blogger.comtag:blogger.com,1999:blog-655962722302095847.post-64291458555459499612016-11-17T13:16:45.537+01:002016-11-17T13:16:45.537+01:00According to "Autism: Current theories and ev...According to "Autism: Current theories and evidence"<br />https://books.google.gr/books?isbn=1603274898<br />Maternal Immune activation could also be linked to periodontal disease which I think has something to do with us.<br />I try to treat periodontal attacks I experience with L reuteri ATCC PTA 5289 plus 17938.<br />In the book there is a conclusion that testing a possible association with autism could also be worthwhile.Anonymoushttps://www.blogger.com/profile/16138974464162606874noreply@blogger.com